TinsyGLP-1 Pill Side Effects: A Symptom Diary for Pills and Shots
GLP-1 pill side effects on the Foundayo™ and Wegovy® pill labels, where a Zepbound® shot fits, and one symptom diary to bring to your prescriber.
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GLP-1 pill side effects are listed on each medicine's official label, and on the two pill labels this article covers, the lists start in the stomach. The Foundayo™ prescribing information names nausea, constipation, diarrhea and vomiting first. The Wegovy® label, which covers the Wegovy® pill and the Wegovy® shot in one document, names nausea, diarrhea, vomiting and constipation first.
If you came here to find out which of Foundayo™, the Wegovy® pill or a Zepbound® shot is easier on the stomach, this page will not tell you. This page does not rank medicines; choosing one is a conversation for your prescriber. What this page can do is help you keep one clear symptom diary, pill or shot, so your prescriber sees your own pattern.
What are GLP-1 pill side effects?
Mostly stomach and gut effects, according to the labels. Foundayo™ (orforglipron) is a daily tablet. Its prescribing information, revised in July 2026, lists these as its most common adverse reactions: nausea, constipation, diarrhea, vomiting, indigestion, stomach pain, headache, a swollen belly, tiredness, burping, acid reflux, gas and hair loss. MedlinePlus asks people to tell their doctor if any of these are severe or do not go away.
Our Foundayo™ daily pill diary goes deeper into the first weeks on that tablet. This article is about keeping one diary that still works if your plan involves a different pill, or a shot.
What are Wegovy® pill side effects?
The Wegovy® Medication Guide lists the most common side effects for Wegovy® as a whole: nausea, diarrhea, vomiting, constipation, stomach pain, changes in skin sensations, headache, tiredness, upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, heartburn and hair loss. The prescribing information adds that in its trial of Wegovy® tablets, the common side effects were similar in type to those listed for the injection.
The pill also comes with its own instructions about how to take each tablet, set out in the label. A diary line about whether the morning went as your prescriber described can be useful context next to a rough day. Follow the leaflet and your prescriber for the routine itself.
Where does a Zepbound® shot fit?
Zepbound® (tirzepatide) is a weekly injection, not a pill, but it often appears in the same searches. Its prescribing information, revised in August 2026, lists nausea, diarrhea, vomiting, constipation, stomach pain, indigestion, injection site reactions, tiredness, allergic reactions, burping, hair loss and acid reflux as its most common adverse reactions. MedlinePlus also lists decreased appetite.
A weekly shot changes the rhythm of the diary, not its purpose. A diary entry can include both the symptom date and the date of your last shot, ready to show your prescriber. Our Zepbound® first week guide covers the start of that rhythm.
Can you compare side effects between a GLP-1 pill and a shot?
Not from these labels, and not from a diary. This page does not use the labels to rank medicines. A diary describes you on one medicine at a time, which is exactly what makes it useful to your prescriber.
If your prescriber changes your medicine or the way you take it, start a new section in your diary with the date. That keeps notes from one medicine from blurring into the next, and it lets your prescriber see what happened after each change. Our guide to pills and shots explains how a daily or weekly routine shapes what is worth writing down.
How do you keep one symptom diary for a pill or a shot?
Keep the same fields every day, and change only the anchor: the time you took your tablet, or the day of your shot.
| What | What to write down |
|---|---|
| The medicine | Its name and the date you started |
| Each dose taken | Pill: day, time and whether it went as your instructions say. Shot: day, time and spot |
| Symptoms | What, when it started and stopped, strength from 0 to 10; on a shot, days since your last one |
| Fluids | Whether you could keep fluids down |
| Other medicines | Everything you take by mouth, and any change |
| Changes | The date of any change your prescriber makes |
| Questions | Anything to ask at your next visit |
Other medicines earn their own line. The Wegovy® Medication Guide says it slows stomach emptying and can affect medicines that need to pass through the stomach quickly, and asks you to keep a list of your medicines to show your healthcare provider and pharmacist.
A fictional entry can be this short: "Tablet taken as instructed. Queasy mid-morning, 3 out of 10, gone by lunch. Kept water down. Question: is this expected in week two?" It is an example of the format, not a schedule.
Which symptoms should not wait for your diary?
A diary is for patterns. The Wegovy® Medication Guide calls for contacting a healthcare provider right away for some symptoms; examples from it and the other sources follow:
- Severe stomach pain that will not go away, with or without vomiting, sometimes felt through to the back. The Wegovy® Medication Guide calls for contacting your healthcare provider right away. MedlinePlus for orforglipron and for tirzepatide call for contacting your doctor immediately.
- Signs of a serious allergic reaction, such as swelling of the face, lips, tongue or throat, or trouble breathing or swallowing. MedlinePlus for orforglipron calls for contacting your doctor immediately or getting emergency medical treatment.
- Nausea, vomiting or diarrhea that does not go away. The Wegovy® Medication Guide explains that losing fluids may cause kidney problems and says to tell your healthcare provider right away.
- Pain in the upper stomach, fever, yellowing of the skin or eyes, or clay-colored stools. The same guide lists these as possible gallbladder symptoms to report to your healthcare provider.
These are examples from the sources, not a complete list. Read the Medication Guide for your own medicine.
FAQ: GLP-1 pill side effects
Are GLP-1 pill side effects different from shot side effects?
The labels cannot answer that for you. This page does not use their lists to rank medicines. The Wegovy® label does say its tablet trial showed common side effects similar in type to its injection list. For anything beyond what the labels say, ask your prescriber.
What are the side effects of Foundayo™?
The most common ones on its prescribing information are nausea, constipation, diarrhea, vomiting, indigestion, stomach pain, headache, a swollen belly, tiredness, burping, acid reflux, gas and hair loss. Our Foundayo™ pill diary shows what to note each day.
Do I need a separate diary for each medicine?
No. One diary works, as long as each entry names the medicine and each change your prescriber makes starts with a date. That way your notes stay readable even if your treatment changes over the year.
Should I log symptoms on days without a dose?
You can date each symptom entry and record the date of your last shot, including entries on days with no dose recorded. Bring those notes to your prescriber.
The limits of a diary
Tinsy is a wellness diary, not a medical device. It does not diagnose, treat or give medical advice. Always talk to your prescriber about doses, side effects and anything that worries you.
Tinsy is independent and is not affiliated with, endorsed by or sponsored by Lilly or Novo Nordisk. Foundayo™, Zepbound® and Wegovy® are trademarks of their respective owners.
Keep your diary in Tinsy
You can keep this diary in a notebook. Tinsy keeps the dose side in one place for free: shots and tablets, reminders for your prescribed plan, a calendar and your history, plus a body map for shots. Tinsy Plus adds side effects with severity levels next to your doses, trends and a doctor report (PDF) to bring to your appointments.
